What is PROLIFERATIVE THERAPY?

PROLIFERATIVE THERAPY, also know as PROLOTHERAPY or NON-SURGICAL JOINT
RECONSTRUCTION, is a method of injecting an anesthetic and an irritant into joints, ligaments or
tendons that are weakened, torn or pulled. It is a NON-SURGICAL METHOD BY WHICH LIGAMENTS
AND TENDONS ARE REPAIRED, resulting in strengthening of the weakened connective tissue by USING
THE BODY’S OWN HEALING POWERS.

How does PROLOTHERAPY WORK?
With prolotherapy, an injectate is injected into the lax or torn areas CAUSING A STRESS
INFLAMMATION. This inflammation results in the PROLIFERATIVE CELLS MIGRATING TO THE
WEAKENED AREA, ALLOWING FOR GROWTH OF NEW, STRENGTHENED TISSUES. This is how
prolotherapy provides a mechanism by which the body can work toward healing itself. Prolotherapy HELPS

STIMULATE THE BODY TO MAKE COLLAGEN.
This is accomplished through a series of injections, not of collagen, but of a mild chemical or a natural
irritant such as dextrose (sugar), which stimulates an immune response facilitating the body to produce
collagen naturally. THE IMMUNE RESPONSE IS FACILITATED BECAUSE THE PROCEDURE CAUSES

A STRESS INFLAMMATION (unlike that caused from an infection) and the body responds to this, thereby starting the repair process. The procedure increases the number of fibroblasts, which synthesize collagen.The making of new collagen facilitates tissue repair, which allows for strengthened and restored tendons, ligaments and joints, and ultimately translates into more significant and/or permanent pain relief.
THE ADVANTAGE OF PROLOTHERAPY IS THAT IT DOES NOT INTERFERE WITH THE PATIENT’S
ACTIVITY LEVEL DURING TREATMENT (ACTIVITY CAN CONTINUE AT WORK, EXERCISE AND PLAY),
AND THERE IS NO POSTOPERATIVE RECOVERY TIME.

What is in PROLOTHERAPY INJECTIONS?

Several different types of injections have proven to be successful in prolotherapy (chemical irritants,
osmotic agents, and particulates). Each works in different ways to motivate the body to heal itself through a variety of natural responses. The end result with each injection is the same: FACILITATE HEALING BY BUILDING NEW TISSUE, RESTORING JOINT STABILITY, AND ELIMINATING THE SOURCE OF THE PAIN.
All of the solutions used in prolotherapy ARE A COMBINATION OF ANESTHETIC AND PROLIFERANT so
that they provide a DUAL EFFECT. The anesthetic agent alleviates the “pain trigger,” while at the same
time the proliferant agent begins to strengthen the ligaments and tendons at the trigger points or tender points. The proliferant agents employed have unique qualities and can be used separately or in
combination with each other, depending on the individual needs of each patient. The agents and their
qualities are as follows:

1. -- Chemical irritants include mild chemical irritants and chemotactic agents
• Mild chemical irritants, such as phenol or tannic acid, trigger the healing process by attaching
themselves to the walls of the cells wherever they are injected; this causes an irritation/inflammation that stimulates the body to produce collagen and start the healing process.

• Chemotactic agents are proliferants that attract macrophages directly to the injected area (e.g.,
Morrhuate Sodium, which is a fatty acid derived from cod liver oil and is the most commonly used). These macrophages (cells in the body) “clean up” debris associated with inflammation.

2. -- Osmotic agents work by causing cells to lose water, which leads to inflammation and the subsequent stimulation of the healing response; dextrose and glycerin are two of the main ingredients in standard prolotherapy solutions.

3. -- Particulates such as pumice flour are microscopic particles that attract macrophages. The
macrophages secrete growth factors that result in collagen production.Sometimes cofactors, such as the anti-oxidant mineral manganese or a combination of glucosamine sulfate and chondroitin sulfate, are believed to aid in the repair of arthritic joints or degenerative discs.

DESPITE THE ENORMOUS SUCCESS OF THE COMPOUNDS DESCRIBED ABOVE, THE MOST
EXCITING ADVANCES IN PROLOTHERAPY MAY BE JUST AROUND THE CORNER, IN THE FORM OF
INJECTABLE GROWTH FACTORS SUCH AS THOSE USED IN OUR PLATELET RICH PLASMA
INJECTIONS; THIS NEW TECHNOLOGY BRINGS US ONE STEP CLOSER TO STEM CELL THERAPY.
HOW LONG will the effects of treatment last?Because the therapy stimulates the body to create new healthy tissue, the EFFECTS ARE CONSIDERED
PERMANENT. RESULTS ARE NOT SEEN IMMEDIATELY, as IT TAKES MONTHS FOR THE PROCESS
TO FULLY MATURE.Are there any SIDE EFFECTS with prolotherapy?Some people may have sensitivity to the proliferative agent and/or the anesthetic, as evidenced by swelling, headache, nausea and tiredness. This reaction is only temporary as it rarely lasts longer than two to four days after the injection. However, experiencing soreness and stiffness a couple of days afterward is normal. It is best to avoid the use of aspirin and anti-inflammatories for post-injection pain and soreness, as these medications interfere with the healing process.

HOW MANY TREATMENTS are required to receive the maximum benefit?
This is an individual matter depending on many factors. The goal of prolotherapy is to help each patient optimize return to function through proper therapy and exercise. The maximum benefits are achieved
when full strength and endurance are reached and posture is improved. The degree of ligament/joint laxity and underlying arthritis will impact the number of treatments. In general, we recommend starting with 5-6 sessions of injections performed at 3-4 week intervals. We then recommend waiting three months to determine if further injections are indicated.
Unlike steroid injections, the benefits of prolotherapy evolve gradually, thus patience is encouraged with the healing process; it is beneficial to set reasonable expectations relating to the time frame for healing.

The ultimate goal of prolotherapy is to allow each patient to be able to do more physical activity with less pain.

Contact for inquiries and Orders
Dr Jethro
Tel: +44 7946876310 or +1 (213) 534-6894
Email jethrointermidiates AT gmail DOT com

SPECIAL LAUNCHING PRICES: AREA TREATED – COST PER TREATMENT

• Prolotherapy – Low Back 315 Euro / 268 Pounds
• Prolotherapy – Mid Back 315 Euro / 268 Pounds
• Prolotherapy – Neck 315 Euro / 268 Pounds
• Prolotherapy – Knee, Shoulder, or Hip (each) 180 Euro / 153 Pounds
Prolotherapy – TMJ (each) 150 Euro / 128 Pounds
• Prolotherapy – Wrist (each) 180 Euro / 153 Pounds
• Prolotherapy – Pubis 150 Euro / 128 Pounds
• Prolotherapy – Ankle (each) 210 Euro / 179 Pounds
• Prolotherapy – Pelvic Floor 220 – 615 Euro / 187 – 524 Pounds
• Prolotherapy – Heel, Foot, or Hand (each) 150 Euro / 128 Pounds
• Prolotherapy – Elbow (each) 180 Euro / 153 Pounds
• Platelet Rich Plasma (added to above cost of Prolotherapy) 150 Euro / 128 Pounds

or

Prolotherapy – Low Back $700
Prolotherapy – Mid Back $700
Prolotherapy – Neck $700
Prolotherapy – Knee, Shoulder, or Hip (each) $425
Prolotherapy – TMJ (each) $300
Prolotherapy – Wrist (each) $350
Prolotherapy – Ankle (each) $400
Prolotherapy – Pelvic Floor $575-1,225
Prolotherapy – Heel, Foot, or Hand (each) $300
Prolotherapy – Elbow (each) $400


Contact for inquiries and Orders
Dr Jethro
Tel: +44 7946876310 or +1 (213) 534-6894
Email jethrointermidiates AT gmail DOT com

Honestly was just wondering if any of you have ever experienced this.

It started after playing my heavy Purple heart accordion, for hours, following a full tune up. For weeks, I've noticed playing any accordion makes my left arm drop out of it's bellows job.

If the pain is next to your scapula, it could be a pinched nerve due to a vertebral disk problem in your neck. I have the same thing on the right side. It comes and goes; I have learned to manage it. When it acts up, I can use stretches (carefully!) and at home traction to treat it. I mention this because when it started for me, the pain started in the shoulder blade. If it gets real bad, the pain can go down my arm all the way to my hand. If your issue is due to a disk problem,take heart. It usually resolves on its own, given time.