I play almost everything lefthanded, guitar, mandolin, pedal steel{try and find one of them lefthanded}, and fiddle, but having taken piano lessons, I don't have a problem playing righthanded accordions. In fact it would seem really strange to play one that way.Besides, it's nice to be able to pick up at least one instrument that belongs to a righthander and be able to play it. Did I mention that I play harmonicas right side up??