First:
Anything than octave or unison tuning is by definition "wet"


If you have a 2 reed or 3 or 4 reed box tuned unison or dry, you have a concertina sound.

I like some degree of "wet" so that my boxes don't sound like concertinas.
Also

There is a thing called "difference tuning" Meaning anything flat or sharp of (A440) or your base tuning will give you more "presence" and believe it or not more "projection" and volume"

And of course this has zip all to do with "Cajun" or "Pythagorean" or "just" tuning or 12 TET tuning.